THE EFFECT OF BIOLOGICALLY ACTIVE SUBSTANCES ON THE BODY'S ANTIOXIDANT SYSTEM DURING OXIDATIVE STRESS

Abstract

Oxidative stress plays a critical role in the pathogenesis of various chronic
diseases and aging processes. The body’s antioxidant defense system is responsible
for maintaining redox balance and protecting cellular components from oxidative
damage. This study investigates the impact of biologically active substances (BAS),
including vitamins, polyphenols, and other antioxidants, on the functionality and
efficiency of the endogenous antioxidant system during oxidative stress. Utilizing
both in vivo and in vitro models, the study evaluates how BAS modulates oxidative
markers and improves antioxidant responses. The results demonstrate a significant
correlation between BAS intake and enhanced antioxidant enzyme activity,
suggesting their potential therapeutic application in managing oxidative stressrelated conditions.